復合型藥片可降低血壓和膽固醇
A Combination Pill Lowers Blood Pressure and Bad Cholesterol
復合型藥片可降低血壓和膽固醇
Studies have shown that the fewer medicines a person has to take the more likely he or she will take them. Last week, a study was released about a new treatment that combines five medicines for heart disease in one pill. Salim Yusuf of McMaster University in Hamilton, Ontario, Canada was the lead investigator. He presented the findings at the American College of Cardiology Conference in Orlando, Florida.
The experimental drug is known as Polycap. It contains aspirin, a drug to lower cholesterol and three medicines to lower blood pressure. The study was carried out at fifty health centers across India. More than two thousand people between the ages of forty-five and eighty took part in the study. All had at least one risk factor for heart disease. These include high blood pressure, high cholesterol, diabetes or being severely overweight.
The people were divided into nine groups of about two hundred people each. One group took Polycap. The other groups took either a single drug or different combinations of the medicines in the Polycap pill. The study showed that Polycap lowered blood pressure and cholesterol without many side effects. Doctor Yusuf said the single pill, taken once a day, could reduce the average person's risk of heart disease and stroke by about half. The maker of Polycap, Cadila Pharmaceuticals of India, paid for the study.
Cardiovascular diseases of the heart and blood vessels are the number one cause of death around the world. These diseases kill more than seventeen million people every year.
Eighty percent of them are in low and middle income countries. Doctor Yusuf said the single pill treatment could revolutionize heart disease prevention. People would be more likely to take one pill a day than many pills. And one pill would cost less than several pills.
Other heart doctors say heart disease prevention is important but not necessarily with pills. They say patients might be able to get the same results with changes in diet and exercise.
Doctors say that more research on Polycap is needed. They say the drug should be tested on thousands more people, including those in different risk, age and ethnic groups.
研究表明，一個人服用的藥物越少，他就越有可能服用藥物。上周發布了一項關于治療方法的新成果——將治療心臟病的五種藥物置于一片藥中。Salim Yusuf 是麥克馬斯特大學(位于加拿大安大略省漢密爾頓市)的首席調查員。他在佛羅里達，奧蘭多市舉行的美國心臟病學院年會上展示了自己的研究成果。
這個實驗藥物就是Polycap。該藥物含有阿司匹林，一種降低膽固醇的藥物和三種降低血壓的藥物。這項研究是在印度50個健康中心進行的。兩千多個年齡在45歲到80歲的人參加了這項研究。所有受試者至少有一個患心臟病的風險因素，比如高血壓，高膽固醇，糖尿病或嚴重超重。
受試者被分成九組，每組大約兩百人。其中一組服用Polycap，其他組有的單服一種藥物，有的服用Polycap成分經不同搭配形成的藥物。研究結果表明，Polycap可降低血壓和膽固醇，而不會有過多副作用。Yusuf 博士說，每天服用一藥片可以把普通人患心臟病和中風的風險減少一半。Polycap的制造者，印度Cadila 制藥公司資助了這項研究。
心血管疾病是全世界致人死亡的頭號病因。每年有一千五百萬人死于這類疾病。其中80%的人集中在中低收入國家。
博士Yusuf說，只需服用一片藥的治療方法，將會為心臟病的預防帶來一場革命。比起服用多片藥，人們更傾向于服用單片藥，并且單片藥比多片藥花費更少。
其他的心臟科醫生認為，心臟病的預防很重要，但不一定要用藥物。他們說，病人通過改變飲食和加強鍛煉也能得到相同的結果。
醫生們說，對于Polycap還需要更多的研究，并且還需要在上千人身上測試，受試者包括那些處于不同風險期，年齡段和民族的人。
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